Wrote Letter L-056 of 1677-05-14 to Henry Oldenburg about muscles, blood, the movement of fluids in fruit, moxa, and cotton

Date: 
May 14, 1677
Standard reference information
L-number: 
L-056
Leeuwenhoek's number: 
20
Collected Letters number: 
32
Collected Letters volume: 
2

Text of the letter in the original Dutch and in English translation from Alle de Brieven. The Collected Letters at the DBNL - De Digitale Bibliotheek voor de Nederlandse Letteren. A Latin translation was published in Hooke's posthumous Philosophical Experiments and Observations (1726) titled (in English) "Mr. Lewenhoek's Letter to Mr. Oldenburg, received from Dr. Crowe, Aug. 14, 1682. Of the Fibres of Muscles, Dura Mater, Brain, and Moxa."

The original manuscript on ten folio pages, written and signed by Leeuwenhoek, is preserved at the Royal Society (MS. 1856. Early Letters L1.27). Oldenburg's English translation is Early Letters L1.28.

An excerpt was published in Philosophical Transactions, vol. 12, no. 136, dated 25 June 1677. See Publication history below.


Leeuwenhoek wrote this letter to Henry Oldenburg, complying with his request of February 22, about muscles. This letter followed up on observations he had reported in June 1674.

He also wrote about:

  • investigating the structure of muscular tissue, the brain and the spinal cord
  • investigating haemolysis (loss of haemoglobin from the red blood-cells)
  • vascular bundles and the movement of fluids in fruits and seeds
  • the effects of moxa, the Chinese remedy against gout, given to him by Constantijn Huygens
  • cotton, in particular, its usefulness for bandaging

As usual, he asked for feedback.

The photo below of Leeuwenhoek's handwritten manuscript is from the first of the four volumes of Leeuwenhoek's original letters in the archives of the Royal Society. The photo was taken by Mike Peel < MikePeel.net > and is available on Wikimedia Commons.

The smaller piece of paper labeled 22a has the title of the letter as it appeared in Philosophical Transactions no. 136 and the beginning of the English translation.