Began series of experiments to observe microbes

Date: 
April 24, 1676

Began series of infusions of pepper and other spices in which, over the following five months, he observed microbes. His letter of October 9 chronicled 145 separate observations, ending on September 19.

This first observation, Pepper 1, involved 3 oz of whole pepper that had been steeping in snow water for 3 weeks. It was full of little creatures.

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